For academic use only.
    For commercial use, please contact Nooriel Banayan (, John F. Hunt (, or Columbia Science and Technology Ventures (
    Probablistic Crystallization Engineering & Crystal-Packing Analysis Server
    Developed by John Hunt's lab in the Department of Biological Sciences at Columbia University.

    Bulk Lysine-To-Arginine Substitution Webserver

    Upload a CLUSTAL-Omega alignment, and receive recommendations for bulk lysine-to-arginine mutagensis to enhance crystallization propersity.

    Epitope Engineering Webserver

    Upload a FASTA file of homologs with the target protein sequence at the top and a PROF 2 structure prediction for that protein and receive recommendations for crystallization-enhancing point mutations.

    Ramachandran (Glycine/Proline) Engineering Software

    Upload a CLUSTAL-Omega alignment and receive recommendations for glycine-to-X or X-to-proline mutagensis to enhance protein stability. (In development.)